Expression of T helper 17 cells and interleukin 17 in lupus nephritis patients

Influence of 1 Alpha, 25-Dihydroxyvitamin D3 on T Helper 17 Cells and Related Cytokines in Systemic Lupus Erythematosus

Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Emerging data suggests that T helper 17 (Th17) cells play a pathogenic role in SLE and the increased number of these cells correlates with disease activity. In recent years, 1α, 25-dihydroxyvitamin D3 (1,25VitD3) has been considered as an immunomodulatory factor. Objective: To investigate the effect of 1,25VitD3...

The Roles of Interleukin-17 and T Helper 17 Cells in Intestinal Barrier Function

Interleukin-17 and type 17 helper T cells in cancer management and research

Since their recent discovery, T helper 17 (Th17) cells have been frequently detected in the tumor microenvironment of many malignancies, but their clinical implications remain largely unknown. Interleukin-17 (IL-17) detection is commonly related with poor outcomes in colorectal cancers, yet its presence is associated with antitumor responses in ovarian carcinomas. Numerous experimental models i...

the role of interleukin-23 in stability of in vitro t helper-17 cells.

interleukin (il)-17-producing t helper (th)-17 cells have recently been explained as a distinct population  of  cd4+  t  cells which play an important  role in immunity against infectious agents. establishment of persistent phenotype of th17 cells and recognition of lineage-deviating factors are of most attractive goals in modern researches in immunology. although  il-6  and  tgf-β  are  freque...

Expression of interleukin-17 in lesions of erythema multiforme may indicate a role for T helper 17 cells

INTRODUCTION The aim of this study was to evaluate levels of interleukin (IL)-2, IL-6, IL-8, IL-10, IL-17A and interferon γ (IFN-γ) in the serum of patients with erythema multiforme (EM) and to search for the presence of IL-17-expressing cells in lesional samples of EM. MATERIAL AND METHODS A total of 32 patients (22 females and 10 males) diagnosed with EM of the minor or major type were incl...